1183 LUNG PRESSURE VOLUME CURVE IN PREMATURE INFANTS WITH PDA

Variability of end-expiratory lung volume in premature infants.

BACKGROUND Analysis of breath-to-breath variability of respiratory characteristics provides information on the respiratory control. In infants, the control of end-expiratory lung volume (EELV) is active and complex, and it can be altered by respiratory disease. The pattern of EELV variability may reflect the behavior of this regulatory system. OBJECTIVES We aimed to characterize EELV variabil...

Entropy Production and the Pressure–Volume Curve of the Lung

We investigate analytically the production of entropy during a breathing cycle in healthy and diseased lungs. First, we calculate entropy production in healthy lungs by applying the laws of thermodynamics to the well-known transpulmonary pressure-volume (P-V) curves of the lung under the assumption that lung tissue behaves as an entropic spring similar to rubber. The bulk modulus, B, of the lun...

Ventricular pressure-volume curve indices with end-diastolic pressure.

Ventricular pressure-volume curve indices change with end-diastolic pressure.

Many indices have been proposed to describee the diastolic pressure-volume curve mathematically and permit quantification of the elastic properties of the myocardium itself in hopes that changes in the muscle caused by disease would b.e reflected in the diastolic pressure-volume curve. To date, none of the proposed indices has been shown convincingly to discriminate one group of patients from a...

Measurement of alveolar derecruitment in patients with acute lung injury: computerized tomography versus pressure–volume curve

INTRODUCTION Positive end-expiratory pressure (PEEP)-induced lung derecruitment can be assessed by a pressure-volume (P-V) curve method or by lung computed tomography (CT). However, only the first method can be used at the bedside. The aim of the study was to compare both methods for assessing alveolar derecruitment after the removal of PEEP in patients with acute lung injury or acute respirato...